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Hepatitis C Screening, Prevalence and Drug Effectiveness

Hepatitis C is a liver disease caused by infection with the hepatitis C virus. Severity can range from a mild illness lasting a few weeks to a lifelong serious illness. Hepatitis C is usually spread when blood from a person infected with the hepatitis C virus enters the body of someone who is not infected. Many people with hepatitis C virus do not know they are infected, so efforts are underway to increase rates of screening so that people can be treated.

Screening and prevalence for Veterans in VA care

Hepatitis C screening and infection rates for Veterans who received VA care in calendar year (CY) 2012 and in (CY) 2013 were significantly higher for Veterans born from 1945-65 than those born in other periods.

 

Comparative effectiveness of boceprevir and telaprevir-based therapy

This project compared the effectiveness of two hepatitis C drugs, boceprevir and telaprevir, prescribed to 859 U.S. Veterans starting in 2011. The chance of sustained virologic response (SVR) - thought to be a cure - was higher for Veterans on telaprevir.

 

Population Approach to Direct Acting Antivirals

This project describes the comprehensive program established by VA to oversee the use of the new direct-acting antivirals.

This program includes critical analysis of the differences between clinical efficacy observed in clinical trials and clinical effectiveness observed in clinical practice.

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