Hepatitis C is a liver disease caused by infection with the hepatitis C virus. Severity can range from a mild illness lasting a few weeks to a lifelong serious illness. Hepatitis C is usually spread when blood from a person infected with the hepatitis C virus enters the body of someone who is not infected. Many people with hepatitis C virus do not know they are infected, so efforts are underway to increase rates of screening so that people can be treated.
Hepatitis C screening and infection rates for Veterans who received VA care in calendar year (CY) 2012 and in (CY) 2013 were significantly higher for Veterans born from 1945-65 than those born in other periods.
This project compared the effectiveness of two hepatitis C drugs, boceprevir and telaprevir, prescribed to 859 U.S. Veterans starting in 2011. The chance of sustained virologic response (SVR) - thought to be a cure - was higher for Veterans on telaprevir.
This project describes the comprehensive program established by VA to oversee the use of the new direct-acting antivirals.
This program includes critical analysis of the differences between clinical efficacy observed in clinical trials and clinical effectiveness observed in clinical practice.
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